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Immune Cells From the Body Enter the Human Brain During Aging, Stanford Study Finds
For decades, the central dogma of neurobiology has held that the brain is an immunologically privileged site—a sequestered, closed system shielded by the blood-brain barrier. Under this long-standing model, the brain’s specialized immune cells, known as microglia, were thought to be established during embryonic development and to remain a self-sustaining, isolated population throughout an individual’s…
