37 posts
Standard
The label “profound autism” has gained significant traction over the last several years, emerging as a distinct clinical and social descriptor for individuals on the more severe end of the autism spectrum. While the term was intended to draw attention to a population with unique, high-level support needs, its application has remained inconsistent across research…
Standard
The "profound autism" label has gained significant traction in recent years as a descriptive term for individuals on the more severe end of the autism spectrum. However, as the terminology becomes more widespread in clinical, research, and policy discussions, a concerted effort is underway to clarify exactly who qualifies for the designation. The label first…
Standard
The "profound autism" label has gained significant traction in recent years as a descriptive term for individuals situated on the more severe end of the autism spectrum. However, as the terminology becomes more widely used across healthcare, research, and public policy, a concerted effort is underway to clarify precisely who qualifies for the designation. The…
Standard
In a significant breakthrough for neurodegenerative research, scientists at the Icahn School of Medicine at Mount Sinai have unveiled critical new insights into how APOE4—the most potent genetic risk factor for Alzheimer’s disease—actively contributes to brain damage. Through two high-impact studies published in the journals Cell and Cell Stem Cell, researchers have demonstrated that this…
Standard
For decades, the prevailing dogma in neuroscience held that the brain was an "immune-privileged" organ—a secluded fortress isolated from the rest of the body’s defensive systems. This long-standing belief suggested that the brain was largely left to fend for itself, protected by the blood-brain barrier and detached from the systemic surveillance that guards other vital…
Standard
Severe stress experienced during the formative years of childhood does more than just cause emotional distress in the moment; it can fundamentally alter the architecture of the brain, leaving a person significantly more vulnerable to anxiety, depression, and other mood disorders when faced with new challenges later in life. For years, the scientific community has…
Standard
For decades, the central dogma of developmental neurobiology has held that the human brain is a monolithic entity—a single, unified organ arising from a common pool of progenitor cells. Under this established model, the forebrain, midbrain, and hindbrain were thought to trace their lineage back to the same developmental starting point, evolving in tandem as…
